进化医学:微生物、医学和人类对生存的追求

Evolutionary Medicine: Microbes, Medicine, and Humanity's Quest for Survival

Explore the complex relationships between people, pathogens, and our evolutionary past in the first MOOC on evolutionary medicine.

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亚利桑那州立大学
edX
  • 完成时间大约为 4
  • 初级
  • 英语
注:因开课平台的各种因素变化,以上开课日期仅供参考

你将学到什么

An applied understanding of evolutionary principles to human health

Basics about the immune system

Human population variation

How changing environments influence virulence and disease transmission

Biocultural influences on human health

课程概况

Have you ever wondered why we often develop a fever when we get sick? Or a cough? Why do we get cancer? Or the flu? Or allergies? Why do our bodies succumb to disease at all? In this class, we’ll answer these questions by taking a step back in time to consider how our evolutionary past has shaped our health in the present.

Evolutionary medicine integrates an evolutionary biology and anthropology lens with current medical knowledge to enhance our understanding of human health. This class uses topics such as development and aging, human migration, mortality, diseases (infectious, metabolic, and autoimmune), and physiological and behavioral mechanisms of immunity to explore the broad arena of human health within a deep time and global context.

Using this perspective, we will investigate how human populations have co-evolved with microbes for millennia, how our changing environments intersect with our genes to shape phenotypes, how culture and other social factors may influence disease risk, and how to address current emerging health challenges across the globe.

Skills-based course answers :

Taught by faculty in the fields of anthropology, biology, and medicine, this course will prepare students to use evolutionary medicine as a foundation for approaching problems within professional arenas such as medicine, public health, and global health policymaking. Additionally, students can use this course as a skill bridge to other classes related to the applied health sciences.

课程大纲

Week 1: Why do we get sick?

An introduction to sickness behaviors and the immune system through an examination of subject-specific examples such as smallpox, tuberculosis, influenza, and other infectious diseases.

Week 2: Why does selection leave our bodies vulnerable?

The basics of evolutionary theory in the context of how humans have evolved defenses against disease. We consider how our species evolved in environments quite different from our modern world, and how this results in mismatches and tradeoffs in our health.

Week 3: What can our evolutionary past tell us about our health in the present?

An introduction to co-evolution between humans and pathogens, and the factors that affect pathogen virulence and transmission. We’ll examine the “Old Friends” Hypothesis, vaccination, and the emergence of autoimmune and metabolic diseases.

Week 4: How can evolutionary medicine be used to tackle emerging and future health crises?

We’ll examine emerging and waning health threats such as measles, Ebola, and zika in a global and public health context while also considering changing environments and the impact on pathogenicity. In addition, we explore the applications of an evolutionary medicine perspective to global health policymaking.

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